CryoSave: The family stem cell bank.

There are currently over 80 approved therapies where umbilical cord blood stem cells can be used.

CryoSave: The family stem cell bank.

There are currently over 80 approved therapies where umbilical cord blood stem cells can be used.

Over the past 30 years, more than 40,000 cord blood transplants have been performed world-wide.
These transplants have treated blood disorders such as bone marrow failure, haematological malignancies,
inherited blood disorders, immuno-deficiency syndromes and metabolic disorders.

What diseases can currently be treated?


There are currently more than 80 approved therapies, where umbilical cord blood stem cells can be used, for example:

Blood Cancers

  • Acute Lymphoblastic Leukaemia (ALL)
  • Acute Myeloid Leukaemia (AML)
  • Chronic Myeloid Leukaemia (CML)
  • Myelodysplastic Syndrome (MDS)
  • Multiple Myeloma
  • Hodgkin’s Lymphoma
  • Non-Hodgkin’s Lymphoma

Inherited Metabolic Disorders

  • Hurler Disease (MPS type IH)
  • Osteopetrosis
  • Adrenoleukodystrophy
  • Krabbe Disease

Bone Marrow Disorders

  • Aplastic Anaemia,
  • Unspecified Fanconi Anaemia

More Diseases..

Blood Disorders, Bone Marrow Failure Syndrome, Immunodeficiencies and other diseases like Neuroblastoma and Solid Tumours.

Blood Cancers

  • Acute Lymphoblastic Leukaemia (ALL)
  • Acute Myeloid Leukaemia (AML)
  • Chronic Myeloid Leukaemia (CML)
  • Myelodysplastic Syndrome (MDS)
  • Multiple Myeloma
  • Hodgkin’s Lymphoma
  • Non-Hodgkin’s Lymphoma

Inherited Metabolic Disorders

  • Hurler Disease (MPS type IH)
  • Osteopetrosis
  • Adrenoleukodystrophy
  • Krabbe Disease

Bone Marrow Disorders

  • Aplastic Anaemia,
  • Unspecified Fanconi Anaemia

More Diseases..

Blood Disorders, Bone Marrow Failure Syndrome, Immunodeficiencies and other diseases like Neuroblastoma and Solid Tumours.
A comprehensive list of current treatable diseases and therapies can be found on Parents’ Guide to Cord Blood.

The future of regenerative therapy
is exciting and ever-advancing.

What clinical trials are in progress?

Clinical trials currently being conducted, are studying the possibility of using cord stem cells in therapies for example:
  • Acquired hearing loss
  • Alzheimer’s disease
  • Acute Ischemic Stroke
  • Autism Spectrum Disorders
  • Amyotropic Lateral Sclerosis
  • Bronchopulmonary dysplasia
  • Cartilage repair
  • Critical limb ischemia
  • Cerebral Palsy
  • Congenital Diaphragmatic Hernia
  • Congenital Heart Diseases
  • Childhood Hearing Loss
  • Corneal Epithelial Wounds
  • Ulcerative Colitis / Inflammatory Bowel Disease
  • Duchenne Muscular Dystrophy
  • Diabetic Foot Ulcers
  • Diabetes Mellitus (Type I & Type II)
  • Diabetes (Type I)
  • Encephalopathy (neonatal)
  • Epidermolysis Bullosa
  • Fertility
  • Global development delay
  • Graft versus host diseases
  • Glaucoma
  • Hypoplastic left heart syndrome
  • HIV
  • Hydrocephalus
  • Ischemic Stroke (pre/peri-natal)
  • Intraventricular haemorrhage
  • Infant Lung Disease
  • Idiopathic Dilated Cardiomyopathy
  • In-Utero Brain Injury / Stroke
  • Liver Cirrhosis
  • Neurodegenerative Disorders
  • Preterm Neonatal Complications
  • Parkinson’s Disease
  • Rheumatoid Arthritis
  • Severe Hypoxic-ischemic Encephalopathy
  • Systemic Lupus Erythematosus
  • Spinal Cord Injury
  • Skin-Wound / Burns
  • Sweat Gland Diseases / Regeneration

References
• Cairo MS, Rocha V, Gluckman E, et al. Alternative allogeneic donor sources for transplantation for childhood diseases: unrelated cord blood and haploidentical family donora. Biol Blood Marrow Transplant. 2008; 14:44-53. • Cairo MS, Tarek N, Lee DA, et al. Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients. Bone Marrow Transplant. 2016;51:27-33.
• Gluckman E, Ruggeri A, Rocha V, et al. for Eurocord, Netcord, World Marrow Donor Association and National Marrow Donor Program. Family-directed umbilical cord blood banking. Haematolgica. 2001; 96: 1700-1707.
• Mazonson P, Kane M, Colberg K, et al. Prevalence of medical conditions potentially amenable to cellular therapy among families privately storing umbilical cord blood. Matern Child Health J. 2016 (online).
•https://clinicaltrials.gov
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