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February 29, 2024

Unveiling the Promise of Stem Cell Therapy for Traumatic Brain Injury

Dr. Lana du Plessis

Traumatic brain injury (TBI) is a global public health problem that afflicts 55-69 million people worldwide, costs over R7 trillion (US $400 billion or £350 billion) per year, and is a leading cause of injury-related death and disability. Brain injuries can have a wide range of complicated and varied causes, and their symptoms can be extremely mild, severely debilitating, or even fatal. Brain tissue dies when a patient suffers from a cerebral injury because the brain’s blood and oxygen supply is restricted or eliminated.

There are now more than 55 clinical trials looking into the use of cord blood stem cells for cerebral injuries. Since the brain is under pressure as it expands inside the limited area inside the skull, many issues related to traumatic brain injury arise from the destruction of neural tissue. There is growing evidence that cord blood stem cells can penetrate the brain’s protective layers and become part of the brain. These stem cells appear to start healing and repairing as soon as they enter the brain.

Although the exact mechanism by which cord blood stem cells accomplish this is unknown, current hypotheses point to a potent combination of characteristics, including growth factors, anti-inflammatory, and circulation-boosting abilities, as potential solutions. It’s thought that they go straight to the brain’s injured regions to enhance blood flow, regenerate blood vessels, reduce inflammation, and encourage the development of new, healthy neural cells to replace the damaged tissue.

It has been demonstrated that stem cells possess potent anti-inflammatory qualities. The young stem cells have a regulating character on the body through the usage of huge cell quantity transplants. The immuno-effect, which the body is unable to control on its own, can be lessened by them. In particular, MSCs have the ability to prevent the body from overproducing and using T-cells. This impact takes place without endangering the patient’s immune system or making them more susceptible to illness. Following the transplant, the patient’s inflammatory markers significantly decrease, and their immune system returns to normal. There is no need for a second transplant during the years when this anti-inflammatory benefit lasts. For those suffering from autoimmune and degenerative illnesses, this translates into a natural remedy for their symptoms, relief from pain, and an overall improvement in their quality of life. Furthermore, the stem cells will help the body mend more quickly, improving the body’s ability to repair damaged tissue when inflammation is decreased. Because of this, even individuals in good health have resorted to stem cell therapy as a kind of “body maintenance” to control naturally occurring inflammation.

Researchers in 2010 conducted a study that examined mesenchymal stem cells’ potential for treating traumatic brain injury (TBI) and found that to quote them: “Treatment of TBI with hMSCs (Human Mesenchymal Stem Cells) during the acute phase of injury can enhance the neurological functional outcome, and suggest that increased levels of neurotrophic factors in the injured hemisphere leading to decreased neuronal apoptosis is one mechanism by which functional recovery may occur.”

Exploring stem cell therapy for traumatic brain injury represents a significant advancement in medical science. The potential of cord blood stem cells offers hope for millions affected by TBI worldwide. Stem cells’ ability to mitigate inflammation, promote tissue repair, and enhance neurological function presents a multifaceted approach to addressing brain injury complexities. Moreover, the benefits extend beyond acute injury, providing long-term relief for patients with autoimmune and degenerative conditions. As expecting parents, you hold the power to safeguard your child’s future health in a remarkable way.

Consider the extraordinary potential of storing your child’s stem cells. By taking proactive steps now, you can secure a valuable resource that may offer life-changing benefits in the face of unforeseen health challenges down the road. Reach out to us today to learn more about how stem cell storage can pave the way for a healthier tomorrow for your family. Don’t miss this opportunity to invest in your child’s well-being from the very beginning. Contact CryoSave and embark on this journey towards a future of enhanced medical possibilities.

References

  1. Adugna DG, Aragie H, Kibret AA, Belay DG. Therapeutic Application of Stem Cells in the Repair of Traumatic Brain Injury. Stem Cells Cloning. 2022 Jul 13;15:53-61. doi: 10.2147/SCCAA.S369577. PMID: 35859889; PMCID: PMC9289752.
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289752/

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